micro-RNAs dependent regulation of DNMT and HIF1α gene expression in thrombotic disorders
نویسندگان
چکیده
منابع مشابه
ROLE OF micro-RNAs IN THE REGULATION OF GENE EXPRESSION
First miRNAs were described in a flatworm species C. elegans, which led to an understanding of their important regulatory role in cell differentiation (Lee et al., 1993; Wightmanet al., 1993). Another critical step was the discovery of the second miRNA named let-7, which is a product of expression of a heterochronic switch gene in C. elegans (Reinhart et al., 2000). Loss of let-7 gene activity ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-018-38057-6